The Ontario Institute for Cancer Research

Research Grants

May 2002 . November 2002 . May 2003 . November 2003 . May 2004 . May 2005 . November 2005 . May 2006 . November 2006 . May 2007 . November 2007 . November 2008

4th Grant Competition - November, 2003

Fourteen innovative cancer research projects, all with the potential to lead to new agents or better cancer treatments received $7.3 million from the Cancer Research Fund. To date the CRF is providing a total of $26 million in direct support for 57 cancer research projects at 14 sites across Ontario.

Principal Investigator Institution Project Type/Title Award*
       
Allen, Christine University of Toronto Translational: Preclinical validation of novel intraperitoneal drug delivery systems for the treatment of ovarian cancer $435,449
Caldwell, Curtis Sunnybrook & Women's College Health Sciences Centre Clinical: Automated targeting for radiation treatment $326,002
Dick, John University Health Network Translational: Eradication of acute myeloid leukemia stem cells using a monoclonal antibody that ligates the CD44 adhesion molecule $631,386
Done, Susan University Health Network Translational: Identification of molecular alterations leading to malignancy in ductoscopically procured pure mammary epithelial cell populations $651,618
Fleshner, Neil University Health Network Companion: Translational companion study to PRP.1 $641,039
Krishnan, Lakshmi University of Ottawa Translational: Archaeosomes as novel self-adjuvanting vaccine delivery technology for cancer immunotherapy $472,873
Litchfield, David University of Western Ontario Translational: Rational design of novel modulators of cell proliferation $416,386
Mak, Tak University Health Network Translational: Creation and development of an IL13 inhibitor for use in the treatment of Hodgkin's lymphoma $811,661
Minden, Mark University Health Network Clinical: A phase I trial evaluating the administration of decitabine and valproic acid in patients with advanced cancers and refractory or relapsed acute leukemias $437,520
Reilly, Raymond University of Toronto Translational: Investigation of molecular imaging as a tool to probe the response and resistance of breast cancer to treatment with trastuzumab (Herceptin®) $508,097
Roifman, Chaim Hospital for Sick Children Translational: Novel synthetic styryl-acrylonitrile inhibitors of tumour angiogenesis - in vivo translation $512,179
Schimmer, Aaron University Health Network Translational: The identification and characterization of small molecule FAS and TRAIL sensitizers $556,909
Siu, Lillian University Health Network Clinical: A phase I/II trial evaluating the administration of EBV-specific cytotoxic T-lymphocytes following CD45 monoclonal antibody to patients with recurrent or metastatic EBV-positive nasopharyngeal cancer $470,342
Trudel, Suzanne University Health Network Translational: Pre-clinical studies and development of a phase I study of FGFR3 inhibitors for t(4;14) multiple myeloma $481,378

* Includes a value of 20 per cent added for institution overhead.

 

 

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