The Ontario Institute for Cancer Research

Dr. Lincoln Stein

Platform Leader, Informatics and Bio-computing

Platform Description

The technology required for cancer research has become increasingly more complex over the past several years. Accordingly, the development of innovative solutions to handle the large and complicated datasets these new technologies generate has become an essential part of the cancer research process. OICR’s Informatics and Bio-computing Platform, led by Dr. Lincoln Stein, integrates and interprets this data, developing visualization tools to turn raw data into meaningful information for biologists, clinicians and trainees.

Contact Information

Telephone
516-367-8380 (Cold Spring Harbor Laboratory)
416-673-8514 (Ontario Institute for Cancer Research)

Mailing Address 1
Ontario Institute for Cancer Research
MaRS Centre, South Tower
101 College Street, Suite 800
Toronto, Ontario
Canada M5G 0A3 

Mailing Address 2
Cold Spring Harbor Laboratory
Cold Spring Harbor, New York
United States of America 11724

Reactome


Current

2007 - Platform Leader, Informatics and Bio-computing, OICR.
2004 - Professor, Cold Spring Harbor Laboratory.


Background

1998 - 2004   Associate Professor, Cold Spring Harbor Laboratory.
1997   Director Information Systems, CuraGen Corporation.
1992 - 1997 Director, Informatics Core, MIT Genome Center, Whitehead Institute of Biomedical Research, MIT.
1995 - 1997 Instructor, Harvard Medical School, Dept. of Pathology, Brigham and Women’s Hospital.
1989 - 1992   Residency, Anatomic Pathology, Brigham & Women’s Hospital.
1989 PhD, Cell Biology, Harvard University.

 

Selected Bibliography

  1. Liang C, Jaiswal P, Hebbard C, Avraham S, Buckler ES, Casstevens T, Hurwitz B, McCouch S, Ni J, Pujar A, Ravenscroft D, Ren L, Spooner W, Tecle I, Thomason J, Tung C, Wei X, Yap I, Youens-Clark K, Ware D, Stein L. Gramene: a growing plant comparative genomics resource. Nucleic Acids Research. 2007; 1–7.
  2. Schmidt CJ, Romanov M, Ryder O, Magrini V, Hickenbotham M, Glasscock J, McGrath S, Mardis E, Stein LD. Gallus G. Browse: a unified genomic database for the chicken. Nucleic Acids Research, 2007; 1–5.
  3. Vastrik I, D'Eustachio P, Schmidt E, Joshi-Tope G, Gopinath G, Croft D, de Bono B, Gillespie M, Jassal B, Lewis S, Matthews L, Wu G, Birney E, Stein L. Reactome: a knowledge base of biologic pathways and processes. Genome Biology; 2007, 8:R39
  4. Chen N, Mah A, Blacque OE, Chu J, Phgora K, Bakhoum MW, Newbury CRH, Khattra J, Chan S, Go A, Efimenko E, Johnsen R, Phirke P, Swoboda P, Marra M, Moerman, Leroux MR, Baillie DL, Stein LD. Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics. Genome Biology. 2006; 7:R126.
  5. Chen N and Stein LD. Conservation and functional significance of gene topology in the genome of Caenorhabditis elegans. Genome Res. 2006; 16: 606-617.

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